Ward's® Penicillium chrysogenum | Fungi

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Penicillium chrysogenum

Pennicillium chrysogenum is a mold that is widely distributed in nature, and is often found living on foods and in indoor environments. It was previously known as Penicillium notatum. It has rarely been reported as a cause of human disease. It is the source of several β-lactam antibiotics, most significantly penicillin.Other secondary metabolites of P. chrysogenum include various different ...

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xylP Promoter-Based Expression System and Its Use for …

Utilization of filamentous fungi in industrial processes for production of pharmaceuticals is well established. A variety of fungal metabolites are commercially exploited for their antibiotic properties; e.g., the β-lactam antibiotics penicillin and cephalosporin are produced by Penicillium chrysogenum and Acremonium chrysogenum, respectively (3, 16).

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Proteomics Shows New Faces for the Old Penicillin Producer Penicillium

Penicillium chrysogenum : A Versatile Cell Factory for Biotechnology Genome sequence of P. chrysogenum revealed the presence of several nonribosomal peptide synthetases (NRPSs), polyketide synthases (PKSs), and hybrid NRPS-PKS enzymes [57], highlighting the potential of this microorganism to produce other secondary metabolites different from ...

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Engineering of the Filamentous Fungus Penicillium chrysogenum …

Abstract. Penicillium chrysogenum (renamed P. rubens) is the most studied member of a family of more than 350 Penicillium species that constitute the genus. Since the discovery of penicillin by Alexander Fleming, this filamentous fungus is used as a commercial β-lactam antibiotic producer.

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Species-specific PCR to describe local-scale

Penicillium chrysogenum is one of the most numerous eukaryotes on earth with conidia present in concentrations up to 350 m −3 air and 15000 g −1 dust (Beguin & Nolard 1994; Scott 2001).Even sampling from the upper-atmosphere and the Antarctic has detected this ubiquitous fungus (Pitt 2000), and as experienced by Alexander Fleming …

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Penicillium Chrysogenum Merch & Gifts for Sale | Redbubble

High quality Penicillium Chrysogenum-inspired merch and gifts. T-shirts, posters, stickers, home decor, and more, designed and sold by independent artists around the world. All orders are custom made and most ship worldwide within 24 hours.

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University of Groningen Genetic engineering of Penicillium …

CATR 1 I. PENICIllIUM ChrySoGENUM aND SECoNDary METaBolISM 9 I. PENICILLIUM CHRYSOGENUM AND SECONDARY METABOLISM Since the discovery of penicillin by alexander Fleming in the filamen-tous fungus Penicillium notatum, the genus Penicillium has been deeply studied due to its capacity to produce a wide range of secondary me-

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LYFO DISK Penicillium chrysogenum ATCC® 10106™, …

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Penicillium chrysogenum derived from ATCC® 10106™*

Penicillium chrysogenum derived from ATCC® 10106™, SKU: 0178A EZ-Accu Shot™ DETAILS Penicillium chrysogenum derived from ATCC® 10106™*, SKU: 0178K KWIK-STIK™ 6 Pack DETAILS Penicillium chrysogenum derived from ATCC® …

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The Penicillium Chrysogenum Extracellular Proteome. Conversion from …

Penicillium species are important indoor allergens and a limited number of allergens have been reported for these microorganisms (94–99). Among the Penicillium allergens, alkaline or vacuolar serine proteases have been described as the major allergen of P. citrinum, Penicillium brevicompactum, P. chrysogenum, and Penicillium oxalicum .

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Penicillium chrysogenum, Living, Plate

Genus and Species: Penicillium chrysogenum Optimal Growth Medium: Potato Dextrose Agar Optimal Growth Temperature: 25° C Package: Plate Biosafety Level: 1 Fungal Rank: Ascomycetes

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Penicillium chrysogenum

Penicillium chrysogenum has been utilized for commercial production of penicillin for over 50 years. Intensive random mutagenesis and selection, coupled with improvements in fermentation processes have resulted in an increase of approximately 3 orders of magnitude in the titre of penicillin produced by P. chrysogenum ( Backus and Stauffer 1955 ...

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A structure model for hyphal differentiation and penicillin …

The fungi isolated in this study include some internationally well-known species, for instance several species belonging to the genus Penicillium, e.g. P. chrysogenum, which is exploited for the ...

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A Penicillium chrysogenum-based expression system for the …

Background. Small, cysteine-rich and cationic antifungal proteins (APs) from filamentous ascomycetes, such as NFAP from Neosartorya fischeri and PAF from Penicillium chrysogenum, are promising candidates for novel drug development. A prerequisite for their application is a detailed knowledge about their structure–function relation and mode of action, …

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Stoichiometric balance based macrokinetic model for Penicillium

The Embden–Meyerhof–Parnas (EMP) pathway [15], the pentose phosphate pathway (PPP) [16] and the tricarboxylic acid (TCA) cycle [17] are the main pathways in P. chrysogenum fermentation. As illustrated in Fig. 1, glucose enters the cell through the cell wall and is phosphorylated to glucose-6-phosphate (G6P) first.In PPP pathway, a small proportion …

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Synthetic control devices for gene regulation in Penicillium chrysogenum

Abstract Background. Orthogonal, synthetic control devices were developed for Penicillium chrysogenum, a model filamentous fungus and industrially relevant cell factory.In the synthetic transcription factor, the QF DNA-binding domain of the transcription factor of the quinic acid gene cluster of Neurospora crassa is fused to the VP16 activation domain.

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Penicillium chrysogenum | Sigma-Aldrich

Find penicillium chrysogenum and related products for scientific research at Merck

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Penicillin production in industrial strain Penicillium chrysogenum

Strains and culture conditions. All P. chrysogenum strains used in this study are listed in Table 1.Strain P2niaD18 [], whose genome was recently determined by high-throughput sequencing [], served as the fungal recipient for all experiments.Like all commonly used industrial strains, P2niaD18 is a derivate of the former industrial strain Q176, which have underdone …

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Metabolic engineering of β-oxidation in Penicillium chrysogenum …

The filamentous fungus Penicillium chrysogenum is the major industrial producer of penicillin antibiotics. Metabolic engineering has expanded the product range of P. chrysogenum to include other β-lactams. In particular, expression of heterologous genes has enabled the production of industrially relevant precursors for the production of semi-synthetic …

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Microbiologics™ Penicillium chrysogenum ATCC™ …

Each device features a single Penicillium chrysogenum strain in a lyophilized pellet, a reservoir of hydrating fluid and inoculating swab ; For added …

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Species-specific PCR to describe local-scale distributions of four

Introduction. Penicillium chrysogenum is one of the most numerous eukaryotes on earth with conidia present in concentrations up to 350 m −3 air and 15000 g −1 dust (Beguin & Nolard 1994; Scott 2001).Even sampling from the upper-atmosphere and the Antarctic has detected this ubiquitous fungus (), and as experienced by Alexander Fleming (Fleming 1929), …

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Penicillium chrysogenum Allergen Facts, Symptoms, and …

Penicillium Chrysogenum. Penicillium is among the top three most common indoor airborne fungi (along with Aspergillus and Cladosporium). 1,2 These same three molds as well as Alternaria alternata are the species most likely to cause allergy symptoms, which typically occur after allergic individuals inhale mold spores. 3,4 Perhaps most familiar, however, is the Penicillium …

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Microbiologics™ Penicillium chrysogenum Derived from ATCC™ …

Quantitative microorganism preparation of Penicillium chrysogenum that delivers less than 100 CFU per 0.1 mL of hydrated suspension. Supplier: Microbiologics™ 0178A

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Members of the Penicillium chrysogenum velvet complex play …

A velvet multisubunit complex was recently detected in the filamentous fungus Penicillium chrysogenum, the major industrial producer of the β-lactam antibiotic penicillin. Core components of this complex are P. chrysogenum VelA (PcVelA) and PcLaeA, which regulate secondary metabolite production, hyphal morphology, conidiation, and pellet ...

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Penicillium chrysogenum

Penicillium chrysogenum can cause human infection by inhalation, ingestion, or direct contact with contaminated materials or wounds. Host factors: Penicillium chrysogenum is an opportunistic pathogen mainly affecting immunocompromised individuals or those with underlying conditions, such as diabetes, cancer, or organ transplantation. It has a ...

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Penicillium chrysogenum as a fungal factory for feruloyl esterases

Abstract Plant biomass is a promising substrate for biorefinery, as well as a source of bioactive compounds, platform chemicals, and precursors with multiple industrial applications. These applications depend on the hydrolysis of its recalcitrant structure. However, the effective biological degradation of plant cell walls requires several enzymatic groups acting …

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(PDF) A Penicillium chrysogenum-based expression system for …

The Penicillium chrysogenum antifungal protein PAF, a promising tool for the development of new antifungal therapies and fungal cell biology studies. Cell Mol Life Sci. 2008;65:445–54. 3. Kovács L, Virágh M, Takó M, Papp T, Vágvölgyi C, Galgóczy L. Isolation and characterization of Neosartorya fischeri antifungal protein (NFAP ...

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Penicillium Chrysogenum Art for Sale

Shop for penicillium chrysogenum wall art from the world's greatest living artists and iconic brands. All penicillium chrysogenum artwork ships within 48 hours and includes a 30-day money-back guarantee. Choose your favorite penicillium chrysogenum designs and purchase them as wall art, home decor, phone cases, tote bags, and more!

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Taxonomy browser (Penicillium chrysogenum)

Penicillium chrysogenum Taxonomy ID: 5076 (for references in articles please use NCBI:txid5076) current name

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