The purpose of this joint European Respiratory Society (ERS) and European Society for Blood and Marrow Transplantation task force was to develop evidence-based recommendations regarding the treatment of pulmonary cGvHD phenotype bronchiolitis obliterans syndrome in adults. A multidisciplinary group representing specialists in haematology ...
WhatsApp: +86 18221755073The detailed analysis process of this study. Results Differential Expressions of COPD ERS-Related Genes. The clinical characteristics of COPD patients in the public dataset are detailed in Supplementary Table 2.We performed PCA to evaluate the repeatability of data within GSE38974.The results showed that GSE38974 had good data repeatability ().Among the 23 …
WhatsApp: +86 18221755073European Respiratory Journal 2023; DOI: 10.1183/13993003.00442-2023AbstractFrailty is a complex, multidimensional syndrome characterised by a loss of physiological reserves that increases a person's susceptibility to adverse health outcomes. Most knowledge regarding frailty originates from geriatric medicine, however, awareness of its importance as a treatable trait for …
WhatsApp: +86 18221755073Background: Guidelines and standards for diagnosis and management of chronic obstructive pulmonary disease (COPD) have been presented by different national and international societies, but the spirometric criteria for COPD differ between guidelines. Objectives: To estimate prevalence of COPD using the guidelines of the British Thoracic Society (BTS), the European …
WhatsApp: +86 18221755073The Expanded Risk Score in Rheumatoid Arthritis (ERS-RA): performance of a disease-specific calculator in comparison with the traditional prediction scores in the assessment of the 10-year risk of ...
WhatsApp: +86 18221755073ERS Education delivers case-based webinars with the aim to give the audience an opportunity to study real-life clinical cases that have various levels of difficulty and often necessitate a differential diagnosis, to learn and exchange ideas with a panel of respiratory experts and to explore the various diagnosis and treatment options. ...
WhatsApp: +86 18221755073Genistein (GS), an isoflavone compound found in soybean, plays a neuroprotective role in Alzheimer's disease (AD). However, the mechanism of its action remains unclear. Herein, binding ability between GS and GRP78 was predicted by molecular docking, and the effect of GS in vivo and vitro were further studied. In this study, the effects of GS on learning and memory …
WhatsApp: +86 18221755073European Respiratory Journal 2024; DOI: 10.1183/13993003.01727-2023 Chronic graft-versus-host disease (cGvHD) is a common complication after allogeneic haematopoietic stem cell transplantation, characterised by a broad disease …
WhatsApp: +86 18221755073Venue, hotels and travel - ERS Congress 2025 . The ERS Congress 2025 will take place from 27 September to 1 October at RAI Amsterdam, Europaboulevard, 1079 MW Amsterdam. The official hotel partner for the ERS Congress in 2025 is RAI Hotels & Services.
WhatsApp: +86 18221755073Silica exposure has been implicated with the development of various connective tissue diseases. We report a case of 32-year-old stone crusher who developed silicosis with mixed connective …
WhatsApp: +86 18221755073DIAGNOSTIC CRITERIA FOR NTM PULMONARY DISEASE. The 2007 guideline included clinical, radiographic and microbiologic criteria for diagnosing NTM pulmonary disease [].The current guideline also recommends use of these criteria to classify patients as having NTM pulmonary disease ().The significance of NTM isolated from the sputum of individuals who …
WhatsApp: +86 18221755073Among chronic respiratory problems, cough was the most common symptom reported in 26% stone crushers, followed by breathlessness in 20%, phlegm in 18% and chest tightness in 14% stone crushers.
WhatsApp: +86 182217550736. ERS-Related Molecular Mechanism by which Exercise Alleviates NAFLD 6.1. Exercise Reduces Lipid Accumulation in the Liver by Regulating ERS. Lipid ectopic accumulation occurs in the early stage of NAFLD, which leads to ERS in the liver . Unfortunately, ERS further promotes lipid overstore and hepatic steatosis and thus leads to NAFLD [14, 108 ...
WhatsApp: +86 18221755073There are many reasons to suggest that ERS is a critical mediator of proinflammatory response, and extensive findings have confirmed that ERS-induced inflammation contributed to the progression of NAFLD [9, 33]. In this study, it was found that the inflammatory cytokines including IL-1β, IL-6, and TNF-α were all increased in the liver tissues ...
WhatsApp: +86 18221755073Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline focuses on pulmonary disease in adults (without cystic fibrosis or human immunodeficiency virus …
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WhatsApp: +86 18221755073Several studies have indicated that GS might play a role through the ERS-mediated apoptotic pathway. Yeh et al. detected that GS could induce the activation of m-calpain, GADD153, GRP78, and Caspase-12 in hepatocellular carcinoma [11].Yang et al. also found GS could significantly elevate the expression of GRP78, strongly induce the expression of CHOP …
WhatsApp: +86 18221755073Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline focuses on pulmonary disease in adults (without cystic fibrosis or human immunodeficiency virus infection) caused by the most common NTM …
WhatsApp: +86 18221755073Endoplasmic reticulum (ER) is a crucial organelle involved in the generation of proteins in organisms, when protein misfolding leads to accumulation, endoplasmic reticulum stress (ERS) will be triggered (Sun et al., 2022).Pollutants in aquatic environments can lead to apoptosis, necrosis and inflammatory responses by inducing ERS.
WhatsApp: +86 18221755073Living near a concrete crushing facility that generates silica dust can have significant health consequences for individuals in the vicinity. The presence of silica dust in the air and local …
WhatsApp: +86 18221755073Objective: Endoplasmic reticulum stress (ERS) is key in chronic obstructive pulmonary disease (COPD) incidence and progression. This study aims to identify potential ERS-related genes in COPD through bioinformatics analysis and clinical experiments. Methods: We first obtained a COPD-related mRNA expression dataset (GSE38974) from the Gene …
WhatsApp: +86 18221755073Aims of the study: To assess the performance of the Expanded Risk Score in Rheumatoid Arthritis (ERS-RA), a disease-specific cardiovascular disease (CVD) prediction score, in evaluating the 10-year risk, in comparison with other traditional algorithms in patients with rheumatoid arthritis (RA). Methods: Consecutive RA patients, aged 40-75 years, without …
WhatsApp: +86 18221755073We conclude from these findings of the present study that Stone crushers of Karad region exposed to stone dust are prone to develop lung disorders as indicated by abnormal …
WhatsApp: +86 18221755073Adults in U.S. s that are less food secure are significantly more likely to have one or more chronic diseases, and the likelihood increases as food insecurity worsens. Researchers at USDA, Economic Research Service (ERS) recently updated estimates of the fraction of working-age adults with chronic disease in s with incomes at or below …
WhatsApp: +86 18221755073Introduction: Silicosis is a progressive, fibrotic and preventable occupational lung disease. Occupational exposure in stone crushing units to silica particles of size 0.5 to 5µm poses a …
WhatsApp: +86 18221755073Non-tuberculous mycobacteria (NTM) are ubiquitous in the environment. Though there are over 190 NTM species and many more are being reported 1, but only a few NTM species are clinically important to produce pulmonary disease in susceptible individuals.These include Mycobacterium avium complex (MAC), M. kansasii, M. xenopi, M. malmoense and M. genavense among the …
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WhatsApp: +86 182217550731. Introduction. Several studies have documented high to very high levels of mineral dust in worksites—and also the surrounding environment—where stones or rocks are crushed or milled using various types of mechanical crushers to produce aggregates for use in the construction of roads and buildings [1,2,3,4,5,6].In these publications, the main emphasis was …
WhatsApp: +86 18221755073Irumodic Syndrome was a degenerative neurological disorder that caused deterioration of the synaptic pathways. The condition caused confusion, delusions, and eventually death. It could take several years to develop and several more before it proved deadly. The treatment of choice in 2370 was peridaxon, though this only relieved the symptoms. Genetic testing could determine …
WhatsApp: +86 18221755073Background and objectives: The ATS/ERS Task Force on Lung Function Testing recently proposed guidelines for the interpretation of pulmonary function tests and suggested that a reduction in FEV 1 be used for categorizing both obstructive and restrictive abnormalities. This changes the severity stratification algorithm of restrictive patterns diagnosed by spirometry, …
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